Ligand-induced Epidermal Growth Factor Receptor (egfr) Oligomerization Is Kinase-dependent and Enhances Internalization*
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چکیده
OLIGOMERIZATION IS KINASE-DEPENDENT AND ENHANCES INTERNALIZATION* Erik G. Hofman, Arjen N. Bader, Jarno Voortman, Dave J. van den Heuvel, Sara Sigismund, Arie J. Verkleij, Hans C. Gerritsen, and Paul M.P. van Bergen en Henegouwen a Cellular Dynamics, Science Faculty, Utrecht University, Utrecht, the Netherlands; b Molecular Biophysics, Science Faculty, Utrecht University, Utrecht, the Netherlands; c IFOM, The FIRC Institute for Molecular Oncology, Milano, Italy Running head: EGFR oligomerization is kinase dependent Address correspondence to: P.M.P. van Bergen en Henegouwen, Dept. Cellular Dynamics, Institute of Biomembranes, Science Faculty, Utrecht University, Padualaan 8, 3584 CH Utrecht, The Netherlands Phone +31-30-253 3349; Fax +31-30-253 3349; email: [email protected]
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تاریخ انتشار 2010